Functional redundancy is a phenomenon that multiple genes can perform the same function in a biological system.
Functional redundancy among important maize genes gives genetic stability but it has been a major obstacle in maize functional study for a long time.
Thanks to the advance of next generation sequencing technology, genome editing with CRISPR/Cas9 system, and our previous empirical insight on the genome diversity, we tried to address our goal for maize functional genomics with bioinformatics approach.
Here, We developed a web-based tool, CAFRI-Maize, to identify functional redundancy of maize genes and facilitate maize functional study.
By constructing phylogenetic heatmap with reannotated protein domains of B73v5 maize genome and anatomical RNA-Seq data, It can visualize and digitize functional redundancy of each quried gene.
Users can explore the relationships between genes and their functions, which can be used to prioritize candidate genes for functional study.
The CAFRI-Maize manuscript is currently in preparation and will be published in the near future!
• CAFRI-Rice
• CAFRI-Arabidopsis
• CAFRI-Tomato
• CAFRI-Ginseng